No Evidence Links Acetaminophen Use During Pregnancy to Autism, Major Review Finds

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A comprehensive review of 43 scientific studies has found no statistically significant connection between acetaminophen use during pregnancy and an increased risk of autism or other neurodevelopmental disorders in children. The findings, published Friday in The Lancet, effectively counter recent claims suggesting the painkiller (commonly known as Tylenol) poses a threat to fetal brain development.

Conflicting Research Resolved

Previous studies on this topic yielded inconsistent results, with some reporting no association and others indicating minor increases in risk. This new meta-analysis, led by Dr. Asma Khalil of St. George’s Hospital, University of London, provides the most definitive evidence to date. Dr. Khalil stated during a press briefing, “We found no clinically important increase in the risk of autism, A.D.H.D., or intellectual disability.”

First-Line Treatment Remains Safe

Acetaminophen remains the recommended first-line treatment for pain and fever during pregnancy, according to Dr. Khalil. This is because untreated maternal fevers can pose health risks to both the mother and the developing fetus. Medical groups, including the American College of Obstetricians and Gynecologists, have consistently supported this stance.

Political Claims Debunked

The study’s findings directly contradict unsubstantiated claims made by former President Trump and Health Secretary Robert F. Kennedy Jr., who publicly urged pregnant women to avoid acetaminophen based on the unproven theory that it causes autism. These claims are not supported by scientific evidence and ignore the well-established risks of allowing fever to go untreated during pregnancy.

The debate over acetaminophen’s safety in pregnancy highlights the broader issue of misinformation in public health. While some concerns about medication use during pregnancy are valid, spreading unsubstantiated fears without scientific backing can harm both expectant mothers and the public’s trust in medical professionals.

In conclusion, the overwhelming weight of evidence now confirms that acetaminophen use during pregnancy does not demonstrably increase the risk of neurodevelopmental disorders in children, and remains a safe and effective treatment for maternal fever and pain.